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Organic compounds that contain a carbon atom bonded to a halogen atom, and an oxygen atom via a double bond; commonly derived from an oxoacid by replacing a hydroxyl group with a halogen atom.
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Aclidinium Bromide (CAS 320345-99-1) is a long-acting muscarinic antagonist (LAMA) that selectively inhibits muscarinic acetylcholine receptors In binding assays it demonstrates high affinity for M1 M5 receptor subtypes with Ki values of 0 10 0 21 nM Functional studies reveal greater potency at endogenous M2 and M3 receptors with EC50 values of 17 4 nM and 5 3 nM respectively In vivo aclidinium bromide produces a concentration-dependent inhibition of acetylcholine-induced bronchoconstriction (EC50 2 5 23 1 g/mL in anesthetized guinea pigs) and suppresses pilocarpine-induced salivation in rats (EC50 38 g/kg) This compound is widely utilized in respiratory research for evaluating airway smooth muscle modulation via muscarinic receptor antagonism
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Mepenzolate bromide (CAS 76-90-4) is a synthetic quaternary ammonium compound that functions as a muscarinic acetylcholine receptor antagonist By inhibiting parasympathetic neural transmission it reduces gastric secretion and gastrointestinal motility Mepenzolate bromide is generally supplied as a white to light cream powder with high solubility in methanol limited solubility in water and chloroform and minimal solubility in ether This compound is widely employed in research investigating modulation of cholinergic signaling gastrointestinal physiology and autonomic pharmacology and serves as a tool compound for studying antimuscarinic mechanisms in vitro and in vivo
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Mepenzolate bromide (CAS 76-90-4) is a synthetic quaternary ammonium compound that functions as a muscarinic acetylcholine receptor antagonist By inhibiting parasympathetic neural transmission it reduces gastric secretion and gastrointestinal motility Mepenzolate bromide is generally supplied as a white to light cream powder with high solubility in methanol limited solubility in water and chloroform and minimal solubility in ether This compound is widely employed in research investigating modulation of cholinergic signaling gastrointestinal physiology and autonomic pharmacology and serves as a tool compound for studying antimuscarinic mechanisms in vitro and in vivo
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
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Also available in 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel. purity: 98%
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